Original, Peer Reviewed Articles (* indicates senior or co-senior authorship):
1. Schwarzmaier HJ, Yaroslavsky A, Yaroslavsky I, Goldbach T, Kahn T, Ulrich F, Schulze PC, Schober R. Optical properties of native and coagulated human brain structures. SPIE 1997; 2970:492-499.
2. Schulze PC, Thal DR, Bettag M, Schober R. Brain tissue damage and regeneration monitored by ß-amyloid precursor protein in experimental laser-induced interstitial thermotherapy. Neuropathology 1998; 18:55-61.
3. Schulze PC, Kahn T, Harth T, Schwarzmaier HJ, Schober R. Correlation of neuropathologic findings and phase-based MRI temperature maps in experimental laser-induced interstitial thermotherapy. JMRI 1998; 8:115-120.
4. Schulze PC, Adams V, Busert C, Bettag M, Schober R. Effects of laser-induced thermotherapy (LITT) on proliferation and apoptosis of glioma cells in rat brain transplantation tumors. Lasers Surg Med 2002; 30(3):227-32.
5. Hambrecht R, Schulze PC, Gielen S, Linke A, Möbius-Winkler S, Yu J, Kratzsch JJ, Baldauf G, Busse MW, Schubert A, Adams V, Schuler G. Reduction of insulin-like growth factor-I expression in the skeletal muscle of non-cachectic patients with chronic heart failure. J Am Coll Cardiol 2002; 39(7):1175-1181.
6. Adams V, Nehrhoff B, Späte U, Linke A, Schulze PC, Baur A, Gielen S, Hambrecht R, Schuler G. Induction of iNOS expression in skeletal muscle by IL-1b and NF-κB activation: An in vitro and in vivo study. Cardiovasc Res 2002; 54(1):95-104.
7. Schulze PC, Schober R. Fine structure analysis of laser-induced tissue alterations in the central nervous system. Med Laser Appl 2002; 17(1):34-40.
8. Yaroslavsky A, Schulze PC, Yaroslavsky I, Ulrich F, Schober R, Schwarzmaier HJ. Optical properties of normal and coagulated brain structures in vitro in the visible wavelength range. Phys Med Biol. 2002; 47(12):2059-73.
9. Schulze PC, De Keulenaer GW, Yoshioka J, Kassik KA, Lee RT. Vitamin D3 Up-regulated protein-1 (VDUP-1) regulates redox-dependent vascular smooth muscle cell proliferation through interaction with thioredoxin. Circ Res. 2002; 91(8):689-95.
10. Schulze PC, Kluge E, Schuler G, Lauer B. Periprocedural kinetics in serum levels of cytokines and adhesion molecules in patients undergoing elective PTCA and stent implantation: Possible impact on restenosis. Arterioscler Thromb Vasc Biol. 2002; 22(12):2105-2107.
11. Schulze PC, Kratzsch J, Linke A, Möbius-Winkler S, Schoene N, Erbs S, Adams V, Gielen S, Schuler G. Elevated serum levels of leptin and soluble leptin receptor in patients with advanced chronic heart failure. Eur J Heart Failure. 2003; 5(1):33-40.
12. Takahashi T, Lord B, Schulze PC, Fryer R, Sarang SS, Gullans SR, Lee RT. Ascorbic Acid Enhances Differentiation of Embryonic Stem Cells into Cardiac Myocytes. Circulation. 2003; 107, 1912-1916.
13. Schulze PC, Gielen S, Kratzsch J, Linke A, Möbius-Winkler S, Adams V, Hambrecht R, Schuler G. Muscular levels of proinflammatory cytokines correlate with a reduced local expression of insulin-like growth factor-1 in chronic heart failure. Basic Res Cardiol. 2003; 98, 267-274.
14. Adams V, Späte U, Kränkel N, Schulze PC, Hambrecht R, Schuler G. NF-κB Activation in Skeletal Muscle of Patients With Chronic Heart Failure: Correlation with the Expression of Inducible Nitric Oxide Synthase. Eur J Cardiovasc Prevention Rehab. 2003; 10, 273-277.
15. Schulze PC, De Keulenaer GW, Kassik KA, Chen Z, Simon DI, Lee RT. Biomechanically-induced IEX-1 inhibits proliferation of vascular smooth muscle cells and neointima formation. Circ Res. 2003; 93:1210-7.
16. Lammerding J, Schulze PC, Takahashi T, Collins S, Lee RT. Defective nuclear mechanics and mechanotransduction in lamin A/C null cells. J Clin Invest. 2004; 113:370-378.
17. Schulze PC, Linke A, Schoene N, Möbius-Winkler S, Busse M, Hambrecht R, Schuler G. Morphological and Functional Abnormalities of the Skeletal Muscle Correlate With a Reduced Electromyographic Activity in Patients With Chronic Heart Failure. Eur J Cardiovasc Prevention Rehab. 2004; 11(2):155-161.
18. Yoshioka J, Schulze PC, Sylvan JD, Cupesi M, Gannon J, MacGillivray C, Huang H, Lee RT. Thioredoxin Interacting Protein Controls Cardiac Hypertrophy Through Regulation of Thioredoxin Activity. Circulation. 2004; 109(21):2581-6.
19. Schulze PC, Vitzthum HE, Goldammer A, Schneider JP, Schober R. Laser-induced thermotherapy of neoplastic lesions in the brain – Underlying tissue alterations and clinical applicability. Acta Neurochir. 2004; 146(8):803-12.
20. Schulze PC, Takahashi T, Yoshioka J, Zhiheng H, King G, Lee RT. Hyperglycemia Promotes Oxidative Stress through Inhibition of Thioredoxin Function by Txnip. JBC. 2004; 279(29):30369-74.
21. Chen G, Schulze PC, Lee RT, Sylvan JD, Zetter BR, Huang H. Induction of Oxidative Stress by Txnip Promotes the Reverse Transendothelial Migration of Melanoma Cells: A Potential Mechanism for Intravasation. Exp Cell Res. 2004; 300(2):297-307.
22. Linke A, Adams V, Schulze PC, Erbs S, Gielen S, Fiehn E, Möbius-Winkler S, Schubert A, Schuler G, Hambrecht R. Anti-oxidative Effects of Exercise Training in Patients With Chronic Heart Failure: Increase of Radical Scavenger Enzyme Activity in The Skeletal Muscle. Circulation. 2005; 111(14):1763-70.
23. Hambrecht R, Schulze PC, Linke A, Gielen S, Möbius-Winkler S, Schoene N, Erbs S, Adams V, Schuler G. Effects of exercise training on local expression of insulin-like growth factor-I in the skeletal muscle of patients with chronic heart failure. Eur J Cardiovasc Prevention Rehab. 2005 Aug; 12(4):401-6.
24. Lammerding J, Hsiao J, Schulze PC, Kozlov S, Stewart CL, Lee RT. Abnormal Nuclear Shape and Impaired Mechanotransduction in Emerin-Deficient Cells. J Cell Biol. 2005; 170(5):781-91.
25. Schulze PC, Fang J, Kassik KA, Gannon J, MacGillivray C, Lee RT, Rosenthal N. Increased Skeletal Muscle Activation of the Ubiquitin-Proteasome Pathway in Chronic Ventricular Dysfunction is Inhibited by Transgenic Overexpression of IGF-1. Circ Res. 2005;97(5):418-26.
26. Schulze PC, Liu H, Choe E, Bloch KD, Lee RT. Nitric Oxide Dependent Suppression of Thioredoxin-Interacting Protein Enhances Thioredoxin Activity. Arterioscler Thromb Vasc Biol. 2006; 26(12):2666-2672.
27. Parikh H, Carlsson E, Johansson LE, Storgaard H, Poulsen P, Saxena R, Ladd C, Schulze PC, Mazzini MJ, Tornqvist H, Ridderstråle H, Altshuler D, Lee RT, Vaag A, Groop LG, Mootha VK. TXNIP: A glucose-inducible, insulin-repressible gene that regulates glucose homeostasis in humans. PLOS Med. 2007; 4(5):e158.
28. Dietrich T, Garcia RI, De Pablo P, Schulze PC, Hoffmann K. The effects of cigarette smoking on CRP concentrations in men and women and its modification by exogenous oral hormones in women. Eur J Cardiovasc Prev Rehabil. 2007; 14:694-700.
29. Yoshioka J, Imahashi K, Chutkow WA, Burds AA, Gannon J, Huang H, Schulze PC, MacGillivray C, Gabel SA, Murphy E, Lee RT. Targeted Deletion of Thioredoxin-Interacting Protein Prevents Cardiac Dysfunction in Response to Pressure Overload. Circ Res. 2007; 101(12):1328-38.
30. Duscha BD, Schulze PC, Robbins JL, Forman DE. Implications of chronic heart failure on peripheral vasculature and skeletal muscle before and after exercise training. Heart Fail Rev. 2008; 13(1):21-37.
31. Nichols JH, Samy B, Nasir K, Fox CS, Schulze PC, Bamberg F, Hoffmann U. Volumetric Measurement of Pericardial Adipose Tissue from Contrast-Enhanced Coronary CTA: A Reproducibility Study. J Cardiovasc Comput Tomogr. 2008; 2(5):288-95.
32. Duscha BD, Schulze PC, Robbins JL, Forman DE. Implications of chronic heart failure on peripheral vasculature and skeletal muscle before and after exercise training. Heart Fail Rev. 2008; 13(1):21-37
33. Biolo A, Fisch M, Balog J, Chao T, Schulze PC, Ooi H, Siwik D, Colucci WS. Episodes of Acute Heart Failure Syndrome are Associated with Increased Levels of Troponin and Extracellular Matrix Markers. Circ Heart Fail. 2010; 3(1):44-50
34. *Khawaja T, Greer C, Chokshi A, Chavarria N, Thadani S, Jones M, Schaefle K, Bhatia K, Collado JE, Shimbo D, Einstein AJ, Schulze PC. Epicardial fat volume in patients with left ventricular systolic dysfunction. Am J Cardiol. 2011;108(3):397-401.
35. *Kato TS, Chokshi A, Singh P, Khawaja T, Cheema F, Akashi H, Shahzad K, Iwata S, Homma S, Takayama H, Naka Y, Jorde U, Farr M, Mancini DM, Schulze PC. Effects of continuous-flow versus pulsatile-flow left ventricular assist devices on myocardial unloading and remodeling. Circ Heart Fail. 2011;4(5):546-53.
36. Razani B, Zhang H, Schulze PC, Schilling JD, Verbsky J, Lodhi IJ, Topkara VK, Feng C, Coleman T, Kovacs A, Kelly DP, Saffitz JE, Dorn GW 2nd, Nichols CG, Semenkovich CF. Fatty acid synthase modulates homeostatic responses to myocardial stress. J Biol Chem. 2011;286(35):30949-61.
37. Drosatos K, Drosatos-Tampakaki Z, Khan R, Homma S, Schulze PC, Zannis VI, Goldberg IJ. Inhibition of c-Jun-N-terminal kinase increases cardiac peroxisome proliferator-activated receptor alpha expression and fatty acid oxidation and prevents lipopolysaccharide-induced heart dysfunction. J Biol Chem. 2011;286(42):36331-9.
38. Bokhari S, Raina A, Rosenzweig EB, Schulze PC, Bokhari J, Einstein AJ, Barst RJ, Johnson LL. PET imaging may provide a novel biomarker and understanding of right ventricular dysfunction in patients with idiopathic pulmonary arterial hypertension. Circ Cardiovasc Imaging. 2011;4(6):641-7.
39. Khan RS, Schulze PC, Bokhari S, Goldberg IJ. A sweet heart: Increased cardiac glucose uptake in patients with lipoprotein lipase deficiency. J Nucl Cardiol. 2011;18(6):1107-10.
40. Schulze PC, Biolo A, Gopal D, Shahzad K, Balog J, Fish M, Siwik D, Colucci WS. Dynamics in insulin resistance and plasma levels of adipokines in patients with acute decompensated and chronic stable heart failure. J Card Fail. 2011;17(12):1004-11.
41. *Shahzad K, Chokshi A, Schulze PC. Supplementation of glutamine and omega-3 polyunsaturated Fatty acids as a novel therapeutic intervention targeting metabolic dysfunction and exercise intolerance in patients with heart failure. Curr Clin Pharmacol. 2011;6(4):288-94.
42. *Kato TS, Chokshi A, Singh P, Khawaja T, Iwata S, Homma S, Akashi H, Cheema F, Yang J, Takayama H, Naka Y, Farr M, Mancini D, Schulze PC. Markers of extracellular matrix turnover and the development of right ventricular failure after ventricular assist device implantation in patients with advanced heart failure. J Heart Lung Transplant. 2012;31(1):37-45.
43. Kato TS, Schulze PC, Yang J, Chan E, Shahzad K, Takayama H, Uriel N, Jorde U, Farr M, Naka Y, Mancini D. Pre-operative and post-operative risk factors associated with neurologic complications in patients with advanced heart failure supported by a left ventricular assist device. J Heart Lung Transplant. 2012;31(1):1-8.
44. Kato TS, Farr M, Schulze PC, Maurer M, Shahzad K, Iwata S, Homma S, Jorde U, Takayama H, Naka Y, Gillam L, Mancini D. Usefulness of Two-Dimensional Echocardiographic Parameters of the Left Side of the Heart to Predict Right Ventricular Failure After Left Ventricular Assist Device Implantation. Am J Cardiol. 2012;109(2):246-51.
45. Kato TS, Ota T, Schulze PC, Farr M, Jorde U, Takayama H, Naka Y, Yamashita T, Mancini DM. Asymmetric Pattern of Cerebrovascular Lesions in Patients After Left Ventricular Assist Device Implantation. Stroke. 2012 Mar;43(3):872-4.
46. Baldwin MR, Arcasoy SM, Shah A, Schulze PC, Sze J, Sonett JR, Lederer DJ. Hypoalbuminemia and early mortality after lung transplantation: a cohort study. Am J Transplant. 2012 May;12(5):1256-67.
47. *Khan RS, Kato TS, Chokshi A, Chew M, Yu S, Wu C, Singh P, Cheema FH, Takayama H, Harris C, Reyes-Soffer G, Knöll R, Milting H, Naka Y, Mancini D, Schulze PC. Adipose tissue inflammation and adiponectin resistance in patients with advanced heart failure: correction after ventricular assist device implantation. Circ Heart Fail. 2012 May 1;5(3):340-8.
48. *Yang JA, Kato TS, Shulman BP, Takayama H, Farr M, Jorde UP, Mancini DM, Naka Y, Schulze PC. Liver dysfunction as a predictor of outcomes in patients with advanced heart failure requiring ventricular assist device support: Use of the Model of End-stage Liver Disease (MELD) and MELD eXcluding INR (MELD-XI) scoring system. J Heart Lung Transplant. 2012 Jun;31(6):601-10.
49. *Chokshi A, Cheema FH, Schaefle KJ, Jiang J, Collado E, Shahzad K, Khawaja T, Farr M, Takayama H, Naka Y, Mancini DM, Schulze PC. Hepatic dysfunction and survival after orthotopic heart transplantation: Application of the MELD scoring system for outcome prediction. J Heart Lung Transplant. 2012 Jun;31(6):591-600.
50. *Chokshi A, Drosatos K, Cheema FH, Ji R, Khawaja T, Yu S, Kato T, Khan R, Takayama H, Knöll R, Milting H, Chung CS, Jorde U, Naka Y, Mancini DM, Goldberg IJ, Schulze PC. Ventricular Assist Device Implantation Corrects Myocardial Lipotoxicity, Reverses Insulin Resistance and Normalizes Cardiac Metabolism in Patients with Advanced Heart Failure. Circulation. 2012 Jun 12;125(23):2844-53.
51. Gottumukkala RV, Lv H, Cornivelli L, Wagers AJ, Kwong RY, Bronson R, Stewart GC, Schulze PC, Chutkow W, Wolpert HA, Lee RT, Lipes MA. Myocardial infarction triggers chronic cardiac autoimmunity in type 1 diabetes. Sci Transl Med. 2012 Jun 13;4(138):138ra80.
52. Zavin A, Arena R, Joseph J, Allsup K, Daniels K, Schulze PC, Lecker S, Forman DE. Dynamic assessment of ventilatory efficiency during recovery from peak exercise to enhance cardiopulmonary exercise testing. Eur J Prev Cardiol. 2012. In press.
53. Kato TS, Takayama H, Yoshizawa S, Marboe C, Schulze PC, Farr M, Naka Y, Mancini D, Maurer MS. Cardiac Transplantation in Patients With Hypertrophic Cardiomyopathy. Am J Cardiol. 2012. 110(4):568-74.
54. Liu L, Yu S, Khan RS, Homma S, Schulze PC, Blaner WS, Yin Y, Goldberg IJ. Diacylglycerol acyl transferase 1 overexpression detoxifies cardiac lipids in PPARγ transgenic mice. J Lipid Res. 2012 Aug;53(8):1482-92.
55. Lecker SH, Zavin A, Cao P, Arena R, Allsup K, Daniels KM, Joseph J, Schulze PC, Forman DE. Expression of the irisin precursor fndc5 in skeletal muscle correlates with aerobic exercise performance in patients with heart failure. Circ Heart Fail. 2012;5:812-818
56. *Wu C, Kato TS, Pronschinske K, Qiu S, Naka Y, Takayama H, Schulze-Spate U, Cremers S, Shane E, Mancini D, Schulze PC. Dynamics of bone turnover markers in patients with heart failure and following haemodynamic improvement through ventricular assist device implantation. Eur J Heart Fail. 2012;14:1356-1365
57. *Chavarria N, Kato TS, Khan R, Chokshi A, Collado E, Akashi H, Takayama H, Naka Y, Farr M, Mancini D, Schulze PC. Increased levels of retinol binding protein 4 in patients with advanced heart failure correct after hemodynamic improvement through ventricular assist device placement. Circ J. 2012;76:2148-2152
58. *Akashi H, Kato TS, Takayama H, Naka Y, Farr M, Mancini D, Schulze PC. Outcome of patients with cardiac sarcoidosis undergoing cardiac transplantation-single-center retrospective analysis. Journal of Cardiology. 2012;60:407-410.
59. Uriel N, Jorde UP, Woo Pak S, Jiang J, Clerkin K, Takayama H, Naka Y, Schulze PC, Mancini DM. Impact of long term left ventricular assist device therapy on donor allocation in cardiac transplantation. J Heart Lung Transplant. 2013 Feb;32(2):188-95.
60. *Kim MS, Kato TS, Farr MJ, Wu C, Givens RC, Collado E, Mancini DM, Schulze PC. Hepatic Dysfunction in Ambulatory Patients with Heart Failure – Application of the MELD Scoring System for Outcome Prediction. J Am Coll Cardiol. 2013; 61(22):2253-61.
61. Schulze PC, Jiang J, Yang J, Cheema FH, Schaeffle K, Kato TS, Farr M, Restaino S, Deng M, Maurer M, Horn E, Latif F, Colombo PC, Jorde U, Uriel N, Haythe J, Bijou R, Drusin R, Lee SH, Takayama H, Naka Y, Mancini DM. Preoperative assessment of high-risk candidates to predict survival after heart transplantation. Circ Heart Fail. 2013;6(3):527-34.
62. Hu C, Ge F, Hyodo E, Arai K, Iwata S, Lobdell H 4th, Walewski JL, Zhou S, Clugston RD, Jiang H, Zizola CP, Bharadwaj KG, Blaner WS, Homma S, Schulze PC, Goldberg IJ, Berk PD. Chronic ethanol consumption increases cardiomyocyte fatty acid uptake and decreases ventricular contractile function in C57BL/6J mice. J Mol Cell Cardiol. 2013;59:30-40.
63. Drosatos K, Khan RS, Trent CM, Jiang H, Son NH, Blaner WS, Homma S, Schulze PC, Goldberg IJ. Peroxisome Proliferator-Activated Receptor-γ Activation Prevents Sepsis-Related Cardiac Dysfunction and Mortality In Mice. Circ Heart Fail. 2013;6(3):550-62.
64. Khan RS, Chokshi A, Drosatos K, Jiang H, Yu S, Harris CR, Schulze PC, Homma S, Blaner WS, Shulman GI, Huang LS, Goldberg IJ. Fish oil selectively improves heart function in a mouse model of lipid-induced cardiomyopathy. J Cardiovasc Pharmacol. 2013;61(4):345-54.
65. Wang Ji J, Ye S, Haythe J, Schulze PC, Shimbo D. The risk of adverse events associated with atropine administration during dobutamine stress echocardiography in cardiac transplant patients: A 28-year single-center experience. J Card Fail. 2013;19:762-767
66. Khan RS, Lin Y, Hu Y, Son NH, Bharadwaj KG, Palacios C, Chokshi A, Ji R, Yu S, Homma S, Schulze PC, Tian R, Goldberg IJ. Rescue of heart lipoprotein lipase-knockout mice confirms a role for triglyceride in optimal heart metabolism and function. AJP:Endo Metab. 2013;305:E1339-1347
67. Kato TS, Jiang J, Schulze PC, Jorde U, Uriel N, Kitada S, Takayama H, Naka Y, Mancini D, Gillam L, Homma S, Farr M. Serial echocardiography using tissue Doppler and speckle tracking imaging to monitor right ventricular failure before and after left ventricular assist device surgery. JACC Heart Fail. 2013 Jun;1(3):216-22.
68. *Kato TS, Cheema FH, Yang J, Kawano Y, Takayama H, Naka Y, Farr M, Lederer DJ, Baldwin MR, Jin Z, Homma S, Mancini DM, Schulze PC. Preoperative serum albumin levels predict 1-year postoperative survival of patients undergoing heart transplantation. Circ Heart Fail. 2013;6:785-791
69. *Kato TS, Collado E, Khawaja T, Kawano Y, Kim M, Farr M, Mancini DM, Schulze PC. Value of peak exercise oxygen consumption combined with b-type natriuretic peptide levels for optimal timing of cardiac transplantation. Circ Heart Fail. 2013;6:6-14
70. Kato TS, Stevens GR, Jiang J, Schulze PC, Gukasyan N, Lippel M, Levin A, Homma S, Mancini D, Farr M. Risk stratification of ambulatory patients with advanced heart failure undergoing evaluation for heart transplantation. J Heart Lung Transplant. 2013;32:333-340
71. Kitada S, Kato TS, Thomas SS, Conwell SD, Russo C, Di Tullio MR, Farr M, Schulze PC, Uriel N, Jorde UP, Takayama H, Naka Y, Homma S, Mancini DM. Pre-operative echocardiographic features associated with persistent mitral regurgitation after left ventricular assist device implantation. J Heart Lung Transplant. 2013;32:897-904
72. *Kato TS, Kitada S, Yang J, Wu C, Takayama H, Naka Y, Farr M, Mancini DM, Schulze PC. Relation of preoperative serum albumin levels to survival in patients undergoing left ventricular assist device implantation. Am J Cardiol. 2013;112:1484-1488
73. Zavin A, Arena R, Joseph J, Allsup K, Daniels K, Schulze PC, Lecker S, Forman DE. Dynamic assessment of ventilatory efficiency during recovery from peak exercise to enhance cardiopulmonary exercise testing. Europ J Prevent Cardiol. 2013;20:779-785
74. Armstrong HF, Schulze PC, Kato TS, Bacchetta M, Thirapatarapong W, Bartels MN. Right ventricular stroke work index as a negative predictor of mortality and initial hospital stay after lung transplantation. J Heart Lung Transpl. 2013;32:603-608
75. Zavin A, Daniels K, Arena R, Allsup K, Lazzari A, Joseph J, Schulze PC, Lecker SH, Forman DE. Adiposity facilitates increased strength capacity in heart failure patients with reduced ejection fraction. Int J Cardiol. 2013;167:2468-2471
76. Schulze PC, Jiang J, Yang J, Cheema FH, Schaeffle K, Kato TS, Farr M, Restaino S, Deng M, Maurer M, Horn E, Latif F, Colombo PC, Jorde U, Uriel N, Haythe J, Bijou R, Drusin R, Lee SH, Takayama H, Naka Y, Mancini DM. Preoperative assessment of high-risk candidates to predict survival after heart transplantation. Circ HF. 2013;6:527-534
77. Shin JY, Mendez-Lopez I, Wang Y, Hays AP, Tanji K, Lefkowitch JH, Schulze PC, Worman HJ, Dauer WT. Lamina-associated polypeptide-1 interacts with the muscular dystrophy protein emerin and is essential for skeletal muscle maintenance. Dev Cell. 2013;26:591-603
78. Daniels KM, Zavin A, Allsup K, Joseph J, Arena R, Lazzari AA, Schulze PC, Lecker SH, Brown J, Forman DE. Serum adiponectin in non-cachectic heart failure patients. Int J Cardiol. 2013;168:4363-4364
79. Drosatos-Tampakaki Z, Drosatos K, Siegelin Y, Gong S, Khan S, Van Dyke T, Goldberg IJ, Schulze PC, Schulze-Spate U. Palmitic acid and DGAT1 deficiency enhance osteoclastogenesis while oleic acid-induced triglyceride formation prevents it. J Bone Miner Res. 2014;29:1183-95.
80. Uriel N, Jorde UP, Woo Pak S, Jiang J, Clerkin K, Takayama H, Naka Y, Schulze PC, Mancini DM. Impact of long term left ventricular assist device therapy on donor allocation in cardiac transplantation. J Heart Lung Transplant 2013;32:188-95.
81. Wang Ji J, Ye S, Haythe J, Schulze PC, Shimbo D. The risk of adverse events associated with atropine administration during dobutamine stress echocardiography in cardiac transplant patients: a 28-year single-center experience. J Cardiac Fail 2013;19:762-7.
82. Prosdocimo DA, Anand P, Liao X, Zhu H, Shelkay S, Artero-Calderon P, Zhang L, Kirsh J, Moore D, Rosca MG, Vazquez E, Kerner J, Akat KM, Williams Z, Zhao J, Fujioka H, Tuschl T, Bai X, Schulze PC, Hoppel CL, Jain MK, Haldar SM. Kruppel-like factor 15 is a critical regulator of cardiac lipid metabolism. J Biol Chem. 2014;289:5914-24.
83. Schulze PC, Kitada S, Clerkin K, Jin Z, Mancini DM. Regional Differences in Recipient Waitlist Time and Pre- and Post-Transplant Mortality After the 2006 United Network for Organ Sharing Policy Changes in the Donor Heart Allocation Algorithm. JACC Heart Fail. 2014;2:166-77.
84. *Chung CJ, Wu C, Jones M, Kato TS, Dam TT, Givens R, Templeton DL, Maurer MS, Naka Y, Takayama H, Mancini DM, Schulze PC. Reduced handgrip strength as a marker of frailty predicts clinical outcomes in patients with heart failure undergoing ventricular assist device placement. J Cardiac Fail. 2014;20(5):310-5.
85. Forman DE, Daniels KM, Cahalin LP, Zavin A, Allsup K, Cao P, Santhanam M, Joseph J, Arena R, Lazzari A, Schulze PC, Lecker S. Analysis of Skeletal Muscle Gene Expression Patterns and the Impact of Functional Capacity in Patients with Systolic Heart Failure. J Cardiac Fail. 2014;20(6):422-30.
86. *Kato TS, Lippel M, Naka Y, Mancini DM, Schulze PC. Post-transplant survival estimation using pre-operative albumin levels. J Heart Lung Transplant. 2014;33(5):547-8.
87. Armstrong HF, Schulze PC, Bacchetta M, Thirapatarapong W, Bartels MN. Impact of pulmonary hypertension on exercise performance in patients with interstitial lung disease undergoing evaluation for lung transplantation. Respirology. 2014 Jul;19(5):675-82.
88. *Akat KM, Moore-McGriff D, Morozov P, Brown M, Gogakos T, Correa Da Rosa J, Mihailovic A, Sauer M, Ji R, Ramarathnam A, Totary-Jain H, Williams Z, Tuschl T, Schulze PC. Comparative RNA-sequencing analysis of myocardial and circulating small RNAs in human heart failure and their utility as biomarkers. Proc Natl Acad Sci U S A. 2014;111(30):11151-6.
89. *Enciso JS, Kato TS, Jin Z, Chung C, Yang J, Takayama H, Mancini DM, Schulze PC. Increased Mortality in Cardiac Transplant Recipients with Peripheral Vascular Disease: An Analysis of the United Network of Organ Sharing Database. Am J Cardiol. In Press.
90. *Khawaja T, Chokshi A, Ji R, Kato TS, Xu K, Zizola C, Wu C, Forman DE, Ota T, Takayama H, Naka Y, George I, Mancini DM, Schulze PC. Ventricular Assist Device Implantation Improves Skeletal Muscle Function, Oxidative Capacity and Growth Hormone/Insulin-like Growth Factor-1 Axis Signaling in Patients with Advanced Heart Failure. J Cachexia Sarcopenia Muscle. In Press.
91. *Pronschinske K, Qiu S, Wu C, Kato TS, Khawaja T, Takayama H, Naka Y, Templeton D, George I, Farr MA, Mancini DM, Schulze PC. Neutrophil gelatinase-associated lipocalin and cystatin C for the prediction of clinical events in patients with advanced heart failure and after ventricular assist device placement. J Heart Lung Transplant. In Press.
92. Khawaja T, Greer C, Thadani S, Kato TS, Bhatia K, Konkak A, Bokhari S, Shimbo D, Einstein AJ, Schulze PC. Increased Regional Epicardial Fat Volume Associated with Reversible Myocardial Ischemia in Patients with Suspected Coronary Artery Disease. J Nucl Cardiol. 2014.
Reviews and Editorials:
1. Schulze PC, Gielen S, Schuler G, Hambrecht R. Catabolic alterations in chronic heart failure: Effects of exercise training. Int J Cardiol 2002; 85(1):141-149.
2. Späte U, Schulze PC. Proinflammatory cytokines and skeletal muscle. Curr Opinion Clin Nutr Metab Care. 2004; 7:265-269.
3. Schulze PC, Lee RT. Macrophage-mediated Cardiac Fibrosis. Circ Res. 2004; 95(6):552-3.
4. Schulze PC, Lee RT. Oxidative Stress and Atherosclerosis. Curr Athero Rep. 2005; 7:242-8.
5. Schulze PC, Kratzsch J. Leptin as a New Diagnostic Tool in Chronic Heart Failure. Clin Chim Acta. 2005 Jul 6.
6. Schulze PC, Späte U. IGF-I and muscle wasting in heart failure. Int J Biochem Cell Biol. 2005; 37(10):2023-35.
7. Mazzini MJ, Schulze PC. Proatherogenic pathways leading to vascular calcification. Europ J Radiol. 2006 Mar;57(3):384-9.
8. Schulze PC. Chromogranin A – friend or foe of the failing myocardium? Eur Heart J. 2007 May; 28(9):1052-3.
9. Sarma S, Schulze PC. Exercise as a physiologic intervention to counteract hypertension: can a good idea go bad? Hypertension. 2007; 50(2):294-6
10. Schulze PC. Beneficial Effects of Moderate Exercise in Arterial Hypertension. Hypertension. 2009; 53(4):600-1.
11. Schulze PC. Myocardial lipid accumulation and lipotoxicity in heart failure. J Lipid Res. 2009. 50(11):2137-8.
12. Schulze PC. Protein catabolism and impairment of skeletal muscle insulin signaling in heart failure. Clin Sci 2010.
13. Altin SE, Schulze PC. p53-upregulated modulator of apoptosis (PUMA): a novel proapoptotic molecule in the failing heart. Circulation. 2011;124(1):7-8.
14. Chung CJ, Schulze PC. Exercise as a nonpharmacologic intervention in patients with heart failure. Phys Sportsmed. 2011;39(4):37-43.
15. Altin SE, Schulze PC. Fractalkine: a novel cardiac chemokine? Cardiovasc Res. 2011;92:361-2.
16. Altin SE, Schulze PC. Metabolism of the right ventricle and the response to hypertrophy and failure. Progress in cardiovascular diseases. 2012;55:229-233.
17. Akashi H, Schulze PC. Prognostic scoring systems for patient evaluation before left ventricular assist device implantation. Circ J. 2012;76:1828-1829.
18. Maurer MS, Schulze PC. Exercise intolerance in heart failure with preserved ejection fraction: shifting focus from the heart to peripheral skeletal muscle. J Am Coll Cardiol. 2012;60(2):129-31.
19. Goldberg IJ, Trent C, Schulze PC. Lipid Metabolism and Toxicity in the Heart. Cell Metab. 2012;15(6):805-12.
20. Drosatos K, Schulze PC. Cardiac lipotoxicity: Molecular pathways and therapeutic implications. Curr Heart Fail Report. 2013;10:109-121.
21. Zizola C, Schulze PC. Metabolic and structural impairment of skeletal muscle in heart failure. Heart Fail Rev. 2013;18:623-30.
22. Kato TS, Collado E, Khawaja T, Kawano Y, Kim M, Farr M, Mancini DM, Schulze PC. Value of peak exercise oxygen consumption combined with B-type natriuretic peptide levels for optimal timing of cardiac transplantation. Circ Heart Fail. 2013 May;6(3):e42.
23. Mancini DM, Schulze PC. Heart transplant allocation: in desperate need of revision. J Am Coll Cardiol. 2014;63:1179-81.
24. Kato TS, Schulze PC. Cardiac hepatopathy versus end-stage liver disease: two different entities. J Am Coll Cardiol. 2014;63(17):1810-1.
Case Reports:
1. Schulze PC, Maurer M. Transthyretin Val30Met Mutation in an African American with Cardiac Amyloidosis. Congest Heart Fail. 2010; 16(2):73-6.
2. Schulze PC, Wahla A, Ooi H. Coronary Artery Embolus Complicating Dilated Cardiomyopathy. Congest Heart Fail. Congest Heart Fail. 2009;15(5):247-8.
Books and Chapters:
1. Schulze PC. Untersuchungen optischer und histologischer Grundlagen der laserinduzierten interstitiellen Thermotherapie des Gehirns - Optical and Histological Parameters of Laser-induced Interstitial Thermotherapy (LITT) on Brain Tissue. Dissertation (1999). University Press. Leipzig, Germany.
2. Schulze PC, Vitzthum E, Kahn T, Ogulade V, Schober R. Laser-induced interstitial thermotherapy on brain tumors: imaging and histology (2004). Ecomed, Berlin, Germany.
3. Schulze PC, Rabbani LE. Fibrinolysis in acute myocardial infarction (2011). In Baliga: Cardiology Review.
4. Schulze PC and Toth MJ. Alterations in skeletal muscle in heart failure (2014). In Mann D and Felker M: Heart Failure: A Companion to Braunwald's Heart Disease (Third Edition).
1. Schwarzmaier HJ, Yaroslavsky A, Yaroslavsky I, Goldbach T, Kahn T, Ulrich F, Schulze PC, Schober R. Optical properties of native and coagulated human brain structures. SPIE 1997; 2970:492-499.
2. Schulze PC, Thal DR, Bettag M, Schober R. Brain tissue damage and regeneration monitored by ß-amyloid precursor protein in experimental laser-induced interstitial thermotherapy. Neuropathology 1998; 18:55-61.
3. Schulze PC, Kahn T, Harth T, Schwarzmaier HJ, Schober R. Correlation of neuropathologic findings and phase-based MRI temperature maps in experimental laser-induced interstitial thermotherapy. JMRI 1998; 8:115-120.
4. Schulze PC, Adams V, Busert C, Bettag M, Schober R. Effects of laser-induced thermotherapy (LITT) on proliferation and apoptosis of glioma cells in rat brain transplantation tumors. Lasers Surg Med 2002; 30(3):227-32.
5. Hambrecht R, Schulze PC, Gielen S, Linke A, Möbius-Winkler S, Yu J, Kratzsch JJ, Baldauf G, Busse MW, Schubert A, Adams V, Schuler G. Reduction of insulin-like growth factor-I expression in the skeletal muscle of non-cachectic patients with chronic heart failure. J Am Coll Cardiol 2002; 39(7):1175-1181.
6. Adams V, Nehrhoff B, Späte U, Linke A, Schulze PC, Baur A, Gielen S, Hambrecht R, Schuler G. Induction of iNOS expression in skeletal muscle by IL-1b and NF-κB activation: An in vitro and in vivo study. Cardiovasc Res 2002; 54(1):95-104.
7. Schulze PC, Schober R. Fine structure analysis of laser-induced tissue alterations in the central nervous system. Med Laser Appl 2002; 17(1):34-40.
8. Yaroslavsky A, Schulze PC, Yaroslavsky I, Ulrich F, Schober R, Schwarzmaier HJ. Optical properties of normal and coagulated brain structures in vitro in the visible wavelength range. Phys Med Biol. 2002; 47(12):2059-73.
9. Schulze PC, De Keulenaer GW, Yoshioka J, Kassik KA, Lee RT. Vitamin D3 Up-regulated protein-1 (VDUP-1) regulates redox-dependent vascular smooth muscle cell proliferation through interaction with thioredoxin. Circ Res. 2002; 91(8):689-95.
10. Schulze PC, Kluge E, Schuler G, Lauer B. Periprocedural kinetics in serum levels of cytokines and adhesion molecules in patients undergoing elective PTCA and stent implantation: Possible impact on restenosis. Arterioscler Thromb Vasc Biol. 2002; 22(12):2105-2107.
11. Schulze PC, Kratzsch J, Linke A, Möbius-Winkler S, Schoene N, Erbs S, Adams V, Gielen S, Schuler G. Elevated serum levels of leptin and soluble leptin receptor in patients with advanced chronic heart failure. Eur J Heart Failure. 2003; 5(1):33-40.
12. Takahashi T, Lord B, Schulze PC, Fryer R, Sarang SS, Gullans SR, Lee RT. Ascorbic Acid Enhances Differentiation of Embryonic Stem Cells into Cardiac Myocytes. Circulation. 2003; 107, 1912-1916.
13. Schulze PC, Gielen S, Kratzsch J, Linke A, Möbius-Winkler S, Adams V, Hambrecht R, Schuler G. Muscular levels of proinflammatory cytokines correlate with a reduced local expression of insulin-like growth factor-1 in chronic heart failure. Basic Res Cardiol. 2003; 98, 267-274.
14. Adams V, Späte U, Kränkel N, Schulze PC, Hambrecht R, Schuler G. NF-κB Activation in Skeletal Muscle of Patients With Chronic Heart Failure: Correlation with the Expression of Inducible Nitric Oxide Synthase. Eur J Cardiovasc Prevention Rehab. 2003; 10, 273-277.
15. Schulze PC, De Keulenaer GW, Kassik KA, Chen Z, Simon DI, Lee RT. Biomechanically-induced IEX-1 inhibits proliferation of vascular smooth muscle cells and neointima formation. Circ Res. 2003; 93:1210-7.
16. Lammerding J, Schulze PC, Takahashi T, Collins S, Lee RT. Defective nuclear mechanics and mechanotransduction in lamin A/C null cells. J Clin Invest. 2004; 113:370-378.
17. Schulze PC, Linke A, Schoene N, Möbius-Winkler S, Busse M, Hambrecht R, Schuler G. Morphological and Functional Abnormalities of the Skeletal Muscle Correlate With a Reduced Electromyographic Activity in Patients With Chronic Heart Failure. Eur J Cardiovasc Prevention Rehab. 2004; 11(2):155-161.
18. Yoshioka J, Schulze PC, Sylvan JD, Cupesi M, Gannon J, MacGillivray C, Huang H, Lee RT. Thioredoxin Interacting Protein Controls Cardiac Hypertrophy Through Regulation of Thioredoxin Activity. Circulation. 2004; 109(21):2581-6.
19. Schulze PC, Vitzthum HE, Goldammer A, Schneider JP, Schober R. Laser-induced thermotherapy of neoplastic lesions in the brain – Underlying tissue alterations and clinical applicability. Acta Neurochir. 2004; 146(8):803-12.
20. Schulze PC, Takahashi T, Yoshioka J, Zhiheng H, King G, Lee RT. Hyperglycemia Promotes Oxidative Stress through Inhibition of Thioredoxin Function by Txnip. JBC. 2004; 279(29):30369-74.
21. Chen G, Schulze PC, Lee RT, Sylvan JD, Zetter BR, Huang H. Induction of Oxidative Stress by Txnip Promotes the Reverse Transendothelial Migration of Melanoma Cells: A Potential Mechanism for Intravasation. Exp Cell Res. 2004; 300(2):297-307.
22. Linke A, Adams V, Schulze PC, Erbs S, Gielen S, Fiehn E, Möbius-Winkler S, Schubert A, Schuler G, Hambrecht R. Anti-oxidative Effects of Exercise Training in Patients With Chronic Heart Failure: Increase of Radical Scavenger Enzyme Activity in The Skeletal Muscle. Circulation. 2005; 111(14):1763-70.
23. Hambrecht R, Schulze PC, Linke A, Gielen S, Möbius-Winkler S, Schoene N, Erbs S, Adams V, Schuler G. Effects of exercise training on local expression of insulin-like growth factor-I in the skeletal muscle of patients with chronic heart failure. Eur J Cardiovasc Prevention Rehab. 2005 Aug; 12(4):401-6.
24. Lammerding J, Hsiao J, Schulze PC, Kozlov S, Stewart CL, Lee RT. Abnormal Nuclear Shape and Impaired Mechanotransduction in Emerin-Deficient Cells. J Cell Biol. 2005; 170(5):781-91.
25. Schulze PC, Fang J, Kassik KA, Gannon J, MacGillivray C, Lee RT, Rosenthal N. Increased Skeletal Muscle Activation of the Ubiquitin-Proteasome Pathway in Chronic Ventricular Dysfunction is Inhibited by Transgenic Overexpression of IGF-1. Circ Res. 2005;97(5):418-26.
26. Schulze PC, Liu H, Choe E, Bloch KD, Lee RT. Nitric Oxide Dependent Suppression of Thioredoxin-Interacting Protein Enhances Thioredoxin Activity. Arterioscler Thromb Vasc Biol. 2006; 26(12):2666-2672.
27. Parikh H, Carlsson E, Johansson LE, Storgaard H, Poulsen P, Saxena R, Ladd C, Schulze PC, Mazzini MJ, Tornqvist H, Ridderstråle H, Altshuler D, Lee RT, Vaag A, Groop LG, Mootha VK. TXNIP: A glucose-inducible, insulin-repressible gene that regulates glucose homeostasis in humans. PLOS Med. 2007; 4(5):e158.
28. Dietrich T, Garcia RI, De Pablo P, Schulze PC, Hoffmann K. The effects of cigarette smoking on CRP concentrations in men and women and its modification by exogenous oral hormones in women. Eur J Cardiovasc Prev Rehabil. 2007; 14:694-700.
29. Yoshioka J, Imahashi K, Chutkow WA, Burds AA, Gannon J, Huang H, Schulze PC, MacGillivray C, Gabel SA, Murphy E, Lee RT. Targeted Deletion of Thioredoxin-Interacting Protein Prevents Cardiac Dysfunction in Response to Pressure Overload. Circ Res. 2007; 101(12):1328-38.
30. Duscha BD, Schulze PC, Robbins JL, Forman DE. Implications of chronic heart failure on peripheral vasculature and skeletal muscle before and after exercise training. Heart Fail Rev. 2008; 13(1):21-37.
31. Nichols JH, Samy B, Nasir K, Fox CS, Schulze PC, Bamberg F, Hoffmann U. Volumetric Measurement of Pericardial Adipose Tissue from Contrast-Enhanced Coronary CTA: A Reproducibility Study. J Cardiovasc Comput Tomogr. 2008; 2(5):288-95.
32. Duscha BD, Schulze PC, Robbins JL, Forman DE. Implications of chronic heart failure on peripheral vasculature and skeletal muscle before and after exercise training. Heart Fail Rev. 2008; 13(1):21-37
33. Biolo A, Fisch M, Balog J, Chao T, Schulze PC, Ooi H, Siwik D, Colucci WS. Episodes of Acute Heart Failure Syndrome are Associated with Increased Levels of Troponin and Extracellular Matrix Markers. Circ Heart Fail. 2010; 3(1):44-50
34. *Khawaja T, Greer C, Chokshi A, Chavarria N, Thadani S, Jones M, Schaefle K, Bhatia K, Collado JE, Shimbo D, Einstein AJ, Schulze PC. Epicardial fat volume in patients with left ventricular systolic dysfunction. Am J Cardiol. 2011;108(3):397-401.
35. *Kato TS, Chokshi A, Singh P, Khawaja T, Cheema F, Akashi H, Shahzad K, Iwata S, Homma S, Takayama H, Naka Y, Jorde U, Farr M, Mancini DM, Schulze PC. Effects of continuous-flow versus pulsatile-flow left ventricular assist devices on myocardial unloading and remodeling. Circ Heart Fail. 2011;4(5):546-53.
36. Razani B, Zhang H, Schulze PC, Schilling JD, Verbsky J, Lodhi IJ, Topkara VK, Feng C, Coleman T, Kovacs A, Kelly DP, Saffitz JE, Dorn GW 2nd, Nichols CG, Semenkovich CF. Fatty acid synthase modulates homeostatic responses to myocardial stress. J Biol Chem. 2011;286(35):30949-61.
37. Drosatos K, Drosatos-Tampakaki Z, Khan R, Homma S, Schulze PC, Zannis VI, Goldberg IJ. Inhibition of c-Jun-N-terminal kinase increases cardiac peroxisome proliferator-activated receptor alpha expression and fatty acid oxidation and prevents lipopolysaccharide-induced heart dysfunction. J Biol Chem. 2011;286(42):36331-9.
38. Bokhari S, Raina A, Rosenzweig EB, Schulze PC, Bokhari J, Einstein AJ, Barst RJ, Johnson LL. PET imaging may provide a novel biomarker and understanding of right ventricular dysfunction in patients with idiopathic pulmonary arterial hypertension. Circ Cardiovasc Imaging. 2011;4(6):641-7.
39. Khan RS, Schulze PC, Bokhari S, Goldberg IJ. A sweet heart: Increased cardiac glucose uptake in patients with lipoprotein lipase deficiency. J Nucl Cardiol. 2011;18(6):1107-10.
40. Schulze PC, Biolo A, Gopal D, Shahzad K, Balog J, Fish M, Siwik D, Colucci WS. Dynamics in insulin resistance and plasma levels of adipokines in patients with acute decompensated and chronic stable heart failure. J Card Fail. 2011;17(12):1004-11.
41. *Shahzad K, Chokshi A, Schulze PC. Supplementation of glutamine and omega-3 polyunsaturated Fatty acids as a novel therapeutic intervention targeting metabolic dysfunction and exercise intolerance in patients with heart failure. Curr Clin Pharmacol. 2011;6(4):288-94.
42. *Kato TS, Chokshi A, Singh P, Khawaja T, Iwata S, Homma S, Akashi H, Cheema F, Yang J, Takayama H, Naka Y, Farr M, Mancini D, Schulze PC. Markers of extracellular matrix turnover and the development of right ventricular failure after ventricular assist device implantation in patients with advanced heart failure. J Heart Lung Transplant. 2012;31(1):37-45.
43. Kato TS, Schulze PC, Yang J, Chan E, Shahzad K, Takayama H, Uriel N, Jorde U, Farr M, Naka Y, Mancini D. Pre-operative and post-operative risk factors associated with neurologic complications in patients with advanced heart failure supported by a left ventricular assist device. J Heart Lung Transplant. 2012;31(1):1-8.
44. Kato TS, Farr M, Schulze PC, Maurer M, Shahzad K, Iwata S, Homma S, Jorde U, Takayama H, Naka Y, Gillam L, Mancini D. Usefulness of Two-Dimensional Echocardiographic Parameters of the Left Side of the Heart to Predict Right Ventricular Failure After Left Ventricular Assist Device Implantation. Am J Cardiol. 2012;109(2):246-51.
45. Kato TS, Ota T, Schulze PC, Farr M, Jorde U, Takayama H, Naka Y, Yamashita T, Mancini DM. Asymmetric Pattern of Cerebrovascular Lesions in Patients After Left Ventricular Assist Device Implantation. Stroke. 2012 Mar;43(3):872-4.
46. Baldwin MR, Arcasoy SM, Shah A, Schulze PC, Sze J, Sonett JR, Lederer DJ. Hypoalbuminemia and early mortality after lung transplantation: a cohort study. Am J Transplant. 2012 May;12(5):1256-67.
47. *Khan RS, Kato TS, Chokshi A, Chew M, Yu S, Wu C, Singh P, Cheema FH, Takayama H, Harris C, Reyes-Soffer G, Knöll R, Milting H, Naka Y, Mancini D, Schulze PC. Adipose tissue inflammation and adiponectin resistance in patients with advanced heart failure: correction after ventricular assist device implantation. Circ Heart Fail. 2012 May 1;5(3):340-8.
48. *Yang JA, Kato TS, Shulman BP, Takayama H, Farr M, Jorde UP, Mancini DM, Naka Y, Schulze PC. Liver dysfunction as a predictor of outcomes in patients with advanced heart failure requiring ventricular assist device support: Use of the Model of End-stage Liver Disease (MELD) and MELD eXcluding INR (MELD-XI) scoring system. J Heart Lung Transplant. 2012 Jun;31(6):601-10.
49. *Chokshi A, Cheema FH, Schaefle KJ, Jiang J, Collado E, Shahzad K, Khawaja T, Farr M, Takayama H, Naka Y, Mancini DM, Schulze PC. Hepatic dysfunction and survival after orthotopic heart transplantation: Application of the MELD scoring system for outcome prediction. J Heart Lung Transplant. 2012 Jun;31(6):591-600.
50. *Chokshi A, Drosatos K, Cheema FH, Ji R, Khawaja T, Yu S, Kato T, Khan R, Takayama H, Knöll R, Milting H, Chung CS, Jorde U, Naka Y, Mancini DM, Goldberg IJ, Schulze PC. Ventricular Assist Device Implantation Corrects Myocardial Lipotoxicity, Reverses Insulin Resistance and Normalizes Cardiac Metabolism in Patients with Advanced Heart Failure. Circulation. 2012 Jun 12;125(23):2844-53.
51. Gottumukkala RV, Lv H, Cornivelli L, Wagers AJ, Kwong RY, Bronson R, Stewart GC, Schulze PC, Chutkow W, Wolpert HA, Lee RT, Lipes MA. Myocardial infarction triggers chronic cardiac autoimmunity in type 1 diabetes. Sci Transl Med. 2012 Jun 13;4(138):138ra80.
52. Zavin A, Arena R, Joseph J, Allsup K, Daniels K, Schulze PC, Lecker S, Forman DE. Dynamic assessment of ventilatory efficiency during recovery from peak exercise to enhance cardiopulmonary exercise testing. Eur J Prev Cardiol. 2012. In press.
53. Kato TS, Takayama H, Yoshizawa S, Marboe C, Schulze PC, Farr M, Naka Y, Mancini D, Maurer MS. Cardiac Transplantation in Patients With Hypertrophic Cardiomyopathy. Am J Cardiol. 2012. 110(4):568-74.
54. Liu L, Yu S, Khan RS, Homma S, Schulze PC, Blaner WS, Yin Y, Goldberg IJ. Diacylglycerol acyl transferase 1 overexpression detoxifies cardiac lipids in PPARγ transgenic mice. J Lipid Res. 2012 Aug;53(8):1482-92.
55. Lecker SH, Zavin A, Cao P, Arena R, Allsup K, Daniels KM, Joseph J, Schulze PC, Forman DE. Expression of the irisin precursor fndc5 in skeletal muscle correlates with aerobic exercise performance in patients with heart failure. Circ Heart Fail. 2012;5:812-818
56. *Wu C, Kato TS, Pronschinske K, Qiu S, Naka Y, Takayama H, Schulze-Spate U, Cremers S, Shane E, Mancini D, Schulze PC. Dynamics of bone turnover markers in patients with heart failure and following haemodynamic improvement through ventricular assist device implantation. Eur J Heart Fail. 2012;14:1356-1365
57. *Chavarria N, Kato TS, Khan R, Chokshi A, Collado E, Akashi H, Takayama H, Naka Y, Farr M, Mancini D, Schulze PC. Increased levels of retinol binding protein 4 in patients with advanced heart failure correct after hemodynamic improvement through ventricular assist device placement. Circ J. 2012;76:2148-2152
58. *Akashi H, Kato TS, Takayama H, Naka Y, Farr M, Mancini D, Schulze PC. Outcome of patients with cardiac sarcoidosis undergoing cardiac transplantation-single-center retrospective analysis. Journal of Cardiology. 2012;60:407-410.
59. Uriel N, Jorde UP, Woo Pak S, Jiang J, Clerkin K, Takayama H, Naka Y, Schulze PC, Mancini DM. Impact of long term left ventricular assist device therapy on donor allocation in cardiac transplantation. J Heart Lung Transplant. 2013 Feb;32(2):188-95.
60. *Kim MS, Kato TS, Farr MJ, Wu C, Givens RC, Collado E, Mancini DM, Schulze PC. Hepatic Dysfunction in Ambulatory Patients with Heart Failure – Application of the MELD Scoring System for Outcome Prediction. J Am Coll Cardiol. 2013; 61(22):2253-61.
61. Schulze PC, Jiang J, Yang J, Cheema FH, Schaeffle K, Kato TS, Farr M, Restaino S, Deng M, Maurer M, Horn E, Latif F, Colombo PC, Jorde U, Uriel N, Haythe J, Bijou R, Drusin R, Lee SH, Takayama H, Naka Y, Mancini DM. Preoperative assessment of high-risk candidates to predict survival after heart transplantation. Circ Heart Fail. 2013;6(3):527-34.
62. Hu C, Ge F, Hyodo E, Arai K, Iwata S, Lobdell H 4th, Walewski JL, Zhou S, Clugston RD, Jiang H, Zizola CP, Bharadwaj KG, Blaner WS, Homma S, Schulze PC, Goldberg IJ, Berk PD. Chronic ethanol consumption increases cardiomyocyte fatty acid uptake and decreases ventricular contractile function in C57BL/6J mice. J Mol Cell Cardiol. 2013;59:30-40.
63. Drosatos K, Khan RS, Trent CM, Jiang H, Son NH, Blaner WS, Homma S, Schulze PC, Goldberg IJ. Peroxisome Proliferator-Activated Receptor-γ Activation Prevents Sepsis-Related Cardiac Dysfunction and Mortality In Mice. Circ Heart Fail. 2013;6(3):550-62.
64. Khan RS, Chokshi A, Drosatos K, Jiang H, Yu S, Harris CR, Schulze PC, Homma S, Blaner WS, Shulman GI, Huang LS, Goldberg IJ. Fish oil selectively improves heart function in a mouse model of lipid-induced cardiomyopathy. J Cardiovasc Pharmacol. 2013;61(4):345-54.
65. Wang Ji J, Ye S, Haythe J, Schulze PC, Shimbo D. The risk of adverse events associated with atropine administration during dobutamine stress echocardiography in cardiac transplant patients: A 28-year single-center experience. J Card Fail. 2013;19:762-767
66. Khan RS, Lin Y, Hu Y, Son NH, Bharadwaj KG, Palacios C, Chokshi A, Ji R, Yu S, Homma S, Schulze PC, Tian R, Goldberg IJ. Rescue of heart lipoprotein lipase-knockout mice confirms a role for triglyceride in optimal heart metabolism and function. AJP:Endo Metab. 2013;305:E1339-1347
67. Kato TS, Jiang J, Schulze PC, Jorde U, Uriel N, Kitada S, Takayama H, Naka Y, Mancini D, Gillam L, Homma S, Farr M. Serial echocardiography using tissue Doppler and speckle tracking imaging to monitor right ventricular failure before and after left ventricular assist device surgery. JACC Heart Fail. 2013 Jun;1(3):216-22.
68. *Kato TS, Cheema FH, Yang J, Kawano Y, Takayama H, Naka Y, Farr M, Lederer DJ, Baldwin MR, Jin Z, Homma S, Mancini DM, Schulze PC. Preoperative serum albumin levels predict 1-year postoperative survival of patients undergoing heart transplantation. Circ Heart Fail. 2013;6:785-791
69. *Kato TS, Collado E, Khawaja T, Kawano Y, Kim M, Farr M, Mancini DM, Schulze PC. Value of peak exercise oxygen consumption combined with b-type natriuretic peptide levels for optimal timing of cardiac transplantation. Circ Heart Fail. 2013;6:6-14
70. Kato TS, Stevens GR, Jiang J, Schulze PC, Gukasyan N, Lippel M, Levin A, Homma S, Mancini D, Farr M. Risk stratification of ambulatory patients with advanced heart failure undergoing evaluation for heart transplantation. J Heart Lung Transplant. 2013;32:333-340
71. Kitada S, Kato TS, Thomas SS, Conwell SD, Russo C, Di Tullio MR, Farr M, Schulze PC, Uriel N, Jorde UP, Takayama H, Naka Y, Homma S, Mancini DM. Pre-operative echocardiographic features associated with persistent mitral regurgitation after left ventricular assist device implantation. J Heart Lung Transplant. 2013;32:897-904
72. *Kato TS, Kitada S, Yang J, Wu C, Takayama H, Naka Y, Farr M, Mancini DM, Schulze PC. Relation of preoperative serum albumin levels to survival in patients undergoing left ventricular assist device implantation. Am J Cardiol. 2013;112:1484-1488
73. Zavin A, Arena R, Joseph J, Allsup K, Daniels K, Schulze PC, Lecker S, Forman DE. Dynamic assessment of ventilatory efficiency during recovery from peak exercise to enhance cardiopulmonary exercise testing. Europ J Prevent Cardiol. 2013;20:779-785
74. Armstrong HF, Schulze PC, Kato TS, Bacchetta M, Thirapatarapong W, Bartels MN. Right ventricular stroke work index as a negative predictor of mortality and initial hospital stay after lung transplantation. J Heart Lung Transpl. 2013;32:603-608
75. Zavin A, Daniels K, Arena R, Allsup K, Lazzari A, Joseph J, Schulze PC, Lecker SH, Forman DE. Adiposity facilitates increased strength capacity in heart failure patients with reduced ejection fraction. Int J Cardiol. 2013;167:2468-2471
76. Schulze PC, Jiang J, Yang J, Cheema FH, Schaeffle K, Kato TS, Farr M, Restaino S, Deng M, Maurer M, Horn E, Latif F, Colombo PC, Jorde U, Uriel N, Haythe J, Bijou R, Drusin R, Lee SH, Takayama H, Naka Y, Mancini DM. Preoperative assessment of high-risk candidates to predict survival after heart transplantation. Circ HF. 2013;6:527-534
77. Shin JY, Mendez-Lopez I, Wang Y, Hays AP, Tanji K, Lefkowitch JH, Schulze PC, Worman HJ, Dauer WT. Lamina-associated polypeptide-1 interacts with the muscular dystrophy protein emerin and is essential for skeletal muscle maintenance. Dev Cell. 2013;26:591-603
78. Daniels KM, Zavin A, Allsup K, Joseph J, Arena R, Lazzari AA, Schulze PC, Lecker SH, Brown J, Forman DE. Serum adiponectin in non-cachectic heart failure patients. Int J Cardiol. 2013;168:4363-4364
79. Drosatos-Tampakaki Z, Drosatos K, Siegelin Y, Gong S, Khan S, Van Dyke T, Goldberg IJ, Schulze PC, Schulze-Spate U. Palmitic acid and DGAT1 deficiency enhance osteoclastogenesis while oleic acid-induced triglyceride formation prevents it. J Bone Miner Res. 2014;29:1183-95.
80. Uriel N, Jorde UP, Woo Pak S, Jiang J, Clerkin K, Takayama H, Naka Y, Schulze PC, Mancini DM. Impact of long term left ventricular assist device therapy on donor allocation in cardiac transplantation. J Heart Lung Transplant 2013;32:188-95.
81. Wang Ji J, Ye S, Haythe J, Schulze PC, Shimbo D. The risk of adverse events associated with atropine administration during dobutamine stress echocardiography in cardiac transplant patients: a 28-year single-center experience. J Cardiac Fail 2013;19:762-7.
82. Prosdocimo DA, Anand P, Liao X, Zhu H, Shelkay S, Artero-Calderon P, Zhang L, Kirsh J, Moore D, Rosca MG, Vazquez E, Kerner J, Akat KM, Williams Z, Zhao J, Fujioka H, Tuschl T, Bai X, Schulze PC, Hoppel CL, Jain MK, Haldar SM. Kruppel-like factor 15 is a critical regulator of cardiac lipid metabolism. J Biol Chem. 2014;289:5914-24.
83. Schulze PC, Kitada S, Clerkin K, Jin Z, Mancini DM. Regional Differences in Recipient Waitlist Time and Pre- and Post-Transplant Mortality After the 2006 United Network for Organ Sharing Policy Changes in the Donor Heart Allocation Algorithm. JACC Heart Fail. 2014;2:166-77.
84. *Chung CJ, Wu C, Jones M, Kato TS, Dam TT, Givens R, Templeton DL, Maurer MS, Naka Y, Takayama H, Mancini DM, Schulze PC. Reduced handgrip strength as a marker of frailty predicts clinical outcomes in patients with heart failure undergoing ventricular assist device placement. J Cardiac Fail. 2014;20(5):310-5.
85. Forman DE, Daniels KM, Cahalin LP, Zavin A, Allsup K, Cao P, Santhanam M, Joseph J, Arena R, Lazzari A, Schulze PC, Lecker S. Analysis of Skeletal Muscle Gene Expression Patterns and the Impact of Functional Capacity in Patients with Systolic Heart Failure. J Cardiac Fail. 2014;20(6):422-30.
86. *Kato TS, Lippel M, Naka Y, Mancini DM, Schulze PC. Post-transplant survival estimation using pre-operative albumin levels. J Heart Lung Transplant. 2014;33(5):547-8.
87. Armstrong HF, Schulze PC, Bacchetta M, Thirapatarapong W, Bartels MN. Impact of pulmonary hypertension on exercise performance in patients with interstitial lung disease undergoing evaluation for lung transplantation. Respirology. 2014 Jul;19(5):675-82.
88. *Akat KM, Moore-McGriff D, Morozov P, Brown M, Gogakos T, Correa Da Rosa J, Mihailovic A, Sauer M, Ji R, Ramarathnam A, Totary-Jain H, Williams Z, Tuschl T, Schulze PC. Comparative RNA-sequencing analysis of myocardial and circulating small RNAs in human heart failure and their utility as biomarkers. Proc Natl Acad Sci U S A. 2014;111(30):11151-6.
89. *Enciso JS, Kato TS, Jin Z, Chung C, Yang J, Takayama H, Mancini DM, Schulze PC. Increased Mortality in Cardiac Transplant Recipients with Peripheral Vascular Disease: An Analysis of the United Network of Organ Sharing Database. Am J Cardiol. In Press.
90. *Khawaja T, Chokshi A, Ji R, Kato TS, Xu K, Zizola C, Wu C, Forman DE, Ota T, Takayama H, Naka Y, George I, Mancini DM, Schulze PC. Ventricular Assist Device Implantation Improves Skeletal Muscle Function, Oxidative Capacity and Growth Hormone/Insulin-like Growth Factor-1 Axis Signaling in Patients with Advanced Heart Failure. J Cachexia Sarcopenia Muscle. In Press.
91. *Pronschinske K, Qiu S, Wu C, Kato TS, Khawaja T, Takayama H, Naka Y, Templeton D, George I, Farr MA, Mancini DM, Schulze PC. Neutrophil gelatinase-associated lipocalin and cystatin C for the prediction of clinical events in patients with advanced heart failure and after ventricular assist device placement. J Heart Lung Transplant. In Press.
92. Khawaja T, Greer C, Thadani S, Kato TS, Bhatia K, Konkak A, Bokhari S, Shimbo D, Einstein AJ, Schulze PC. Increased Regional Epicardial Fat Volume Associated with Reversible Myocardial Ischemia in Patients with Suspected Coronary Artery Disease. J Nucl Cardiol. 2014.
Reviews and Editorials:
1. Schulze PC, Gielen S, Schuler G, Hambrecht R. Catabolic alterations in chronic heart failure: Effects of exercise training. Int J Cardiol 2002; 85(1):141-149.
2. Späte U, Schulze PC. Proinflammatory cytokines and skeletal muscle. Curr Opinion Clin Nutr Metab Care. 2004; 7:265-269.
3. Schulze PC, Lee RT. Macrophage-mediated Cardiac Fibrosis. Circ Res. 2004; 95(6):552-3.
4. Schulze PC, Lee RT. Oxidative Stress and Atherosclerosis. Curr Athero Rep. 2005; 7:242-8.
5. Schulze PC, Kratzsch J. Leptin as a New Diagnostic Tool in Chronic Heart Failure. Clin Chim Acta. 2005 Jul 6.
6. Schulze PC, Späte U. IGF-I and muscle wasting in heart failure. Int J Biochem Cell Biol. 2005; 37(10):2023-35.
7. Mazzini MJ, Schulze PC. Proatherogenic pathways leading to vascular calcification. Europ J Radiol. 2006 Mar;57(3):384-9.
8. Schulze PC. Chromogranin A – friend or foe of the failing myocardium? Eur Heart J. 2007 May; 28(9):1052-3.
9. Sarma S, Schulze PC. Exercise as a physiologic intervention to counteract hypertension: can a good idea go bad? Hypertension. 2007; 50(2):294-6
10. Schulze PC. Beneficial Effects of Moderate Exercise in Arterial Hypertension. Hypertension. 2009; 53(4):600-1.
11. Schulze PC. Myocardial lipid accumulation and lipotoxicity in heart failure. J Lipid Res. 2009. 50(11):2137-8.
12. Schulze PC. Protein catabolism and impairment of skeletal muscle insulin signaling in heart failure. Clin Sci 2010.
13. Altin SE, Schulze PC. p53-upregulated modulator of apoptosis (PUMA): a novel proapoptotic molecule in the failing heart. Circulation. 2011;124(1):7-8.
14. Chung CJ, Schulze PC. Exercise as a nonpharmacologic intervention in patients with heart failure. Phys Sportsmed. 2011;39(4):37-43.
15. Altin SE, Schulze PC. Fractalkine: a novel cardiac chemokine? Cardiovasc Res. 2011;92:361-2.
16. Altin SE, Schulze PC. Metabolism of the right ventricle and the response to hypertrophy and failure. Progress in cardiovascular diseases. 2012;55:229-233.
17. Akashi H, Schulze PC. Prognostic scoring systems for patient evaluation before left ventricular assist device implantation. Circ J. 2012;76:1828-1829.
18. Maurer MS, Schulze PC. Exercise intolerance in heart failure with preserved ejection fraction: shifting focus from the heart to peripheral skeletal muscle. J Am Coll Cardiol. 2012;60(2):129-31.
19. Goldberg IJ, Trent C, Schulze PC. Lipid Metabolism and Toxicity in the Heart. Cell Metab. 2012;15(6):805-12.
20. Drosatos K, Schulze PC. Cardiac lipotoxicity: Molecular pathways and therapeutic implications. Curr Heart Fail Report. 2013;10:109-121.
21. Zizola C, Schulze PC. Metabolic and structural impairment of skeletal muscle in heart failure. Heart Fail Rev. 2013;18:623-30.
22. Kato TS, Collado E, Khawaja T, Kawano Y, Kim M, Farr M, Mancini DM, Schulze PC. Value of peak exercise oxygen consumption combined with B-type natriuretic peptide levels for optimal timing of cardiac transplantation. Circ Heart Fail. 2013 May;6(3):e42.
23. Mancini DM, Schulze PC. Heart transplant allocation: in desperate need of revision. J Am Coll Cardiol. 2014;63:1179-81.
24. Kato TS, Schulze PC. Cardiac hepatopathy versus end-stage liver disease: two different entities. J Am Coll Cardiol. 2014;63(17):1810-1.
Case Reports:
1. Schulze PC, Maurer M. Transthyretin Val30Met Mutation in an African American with Cardiac Amyloidosis. Congest Heart Fail. 2010; 16(2):73-6.
2. Schulze PC, Wahla A, Ooi H. Coronary Artery Embolus Complicating Dilated Cardiomyopathy. Congest Heart Fail. Congest Heart Fail. 2009;15(5):247-8.
Books and Chapters:
1. Schulze PC. Untersuchungen optischer und histologischer Grundlagen der laserinduzierten interstitiellen Thermotherapie des Gehirns - Optical and Histological Parameters of Laser-induced Interstitial Thermotherapy (LITT) on Brain Tissue. Dissertation (1999). University Press. Leipzig, Germany.
2. Schulze PC, Vitzthum E, Kahn T, Ogulade V, Schober R. Laser-induced interstitial thermotherapy on brain tumors: imaging and histology (2004). Ecomed, Berlin, Germany.
3. Schulze PC, Rabbani LE. Fibrinolysis in acute myocardial infarction (2011). In Baliga: Cardiology Review.
4. Schulze PC and Toth MJ. Alterations in skeletal muscle in heart failure (2014). In Mann D and Felker M: Heart Failure: A Companion to Braunwald's Heart Disease (Third Edition).
